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Chemical and Biomolecular Analysis – THEMATIC UNITS

HOU > Chemical and Biomolecular Analysis (XBA) > Chemical and Biomolecular Analysis – THEMATIC UNITS

XBA50 MODERN CHEMICAL ANALYSIS

T.U. Code: ΧΒΑ50
Academic Credits (ECTS): 15
T.U. Type: Mandatory
Mandatory : First (1st)
Language of instruction: Greek

T.U. Objective: XBA50 aims to train scientists in the principles, methods, instrumentation, and applications of modern chemical analysis.

Learning Outcomes:Upon successful completion of XBA50, students will be able to:

  • Describe the main methods of instrumental analysis, namely the spectroscopic, electrochemical, chromatographic, radiochemical, and thermal analytical methods, as well as methods of surface chemical analysis
  • Describe the fundamental principles and methods of atomic spectroscopy, molecular spectroscopy, electroanalytical chemistry, and chromatography
  • Describe the fundamental principles and methods of thermal analysis methods,radiochemical methods, particle size determination methods, and automated methods
  • Describe the advantages and drawbacks of each method of analysis
  • Identify the instrumentation of analytical methods
  • Select the most suitable method of analysis for a given case, taking into account its sensitivity, repeatability, and accuracy
  • Calibrate, standardize, and validate instrumental analysis methods

Unit Subjects:

  • Theoretical Foundation of Modern Analytical Chemistry
  • Material and Surface Characterization and Analysis Methods
  • Instrumental Analysis – Instrumentation and Analytical Applications

T.U. Grading:

A. Two (2) Written Assignments over the course of the semester, the average grade of which makes up 20% of the final T.U. grade

Β. Four (4) Educational Activities (E.A.) over the course of the semester, the average grade of which makes up 20% of the final T.U. grade.

C. Final Written Examinations (F.W.E.), the grade of which makes up 60% of the final T.U. grade.

Right to participate in the Final Written Examinations:

Students may participate in the Final Written Examinations (F.W.E.) upon the condition that the Written Assignments and Educational Activities referred to in points A and B have been graded with at least 50% of full marks overall for each point.

Prerequisites: There are no prerequisites for this unit.

Teaching Method: Remote learning, utilizing the H.O.U. Remote Learning Platform, and Group Counseling Meetings (remote GCM, in-person GCM).

XBA51 CONTEMPORARY ISSUES IN APPLIED MOLECULAR BIOLOGY

T.U. Code: ΧΒΑ51
Academic Credits (ECTS): 15
T.U. Type: Mandatory
Semester available: First (1st)
Language of instruction: Greek

T.U. Objective: XBA51 aims to provide students with in-depth knowledge regarding: the evolutionarily developed process of coding and transfer of genetic information from cell to cell, through the structure and function of the genome and its comprehensive, multi-level regulation; the mechanisms that ensure the reliability and accuracy of the transmission and expression of genetic information, repair systems and the modern methodology used to study them; the effects on the genome of environmental factors, which adversely influence life and normal cellular function.

Learning outcomes: Upon successful completion of the unit, students will be able to:

  • Describe the basic structure and functions of the proteins, DNA and RNA.
  • Describe the basic molecular processes of genome replication, transcription, and translation.
  • Identify the mechanisms that regulate the aforementioned processes.
  • Utilize the classical and modern methods of molecular biology.
  • Identify molecular damage at the genome level resulting from mutations, genetic recombination, and epigenetic modifications.
  • Determine the molecular basis of carcinogenesis and the development of various diseases.
  • Define systems biology
  • Describe the contribution of modern bioinformatics analysis to the development of applied molecular biology.

Unit Subjects:

  • Principles of Genomics and Post-Genomics
  • Genome SequencingAnalysis
  • Modern Gene Expression Determination Methods
  • Molecular Oncology – Smart Drugs

T.U. Grading:

A. Two (2) Written Assignments over the course of the semester, the average grade of which makes up 20% of the final T.U. grade

Β. Four (4) Educational Activities (E.A.) over the course of the semester, the average grade of which makes up 20% of the final T.U. grade.

C. Final Written Examinations (F.W.E.), the grade of which makes up 60% of the final T.U. grade.

Right to participate in the Final Written Examinations:

Students may participate in the Final Written Examinations (F.W.E.) upon the condition that the Written Assignments and Educational Activities referred to in points A and B have been graded with at least 50% of full marks overall for each point.

Prerequisites: There are no prerequisites for this unit.

Teaching Method: Remote learning, utilizing the H.O.U. Remote Learning Platform, and Group Counseling Meetings (remote GCM, in-person GCM).

XBA52 SPECIAL ISSUES IN CLINICAL AND APPLIED BIOCHEMISTRY

T.U. Code: ΧΒΑ52
Academic Credits (ECTS): 15
T.U. Type: Mandatory
Semester available: Second (2nd)
Language of instruction: Greek

T.U. Objective: XBA52 aims to provide: a general overview and understanding of the basic concepts of Clinical and Applied Biochemistry, concerning basic principles of the structure and function of the macromolecules that comprise the cell, and the experimental approaches utilized in their study; additionally, in-depth study of the cellular biochemical pathways,the interconnections between them, and the role environmental conditions play in the appearance of biochemical imbalances that lead to clinical symptoms. Students will be familiarized with modern applications in Clinical Biochemistry and Pathobiochemistry regarding samples, quality control, biomarkersand diagnostic tests.

Learning outcomes: Upon successful completion of the unit, students will be able to:

  • Describe the concepts, terms, and applications of the science of Clinical and Applied Biochemistry.
  • Describe the basic principles of human Pathobiochemistry and its connection with nutrition.
  • Explain the basic biochemical pathways of the cell and the interactions between them.
  • Identify the classical and modern methods of Clinical and Applied Biochemistry, and apply their quality control methods.
  • Recognize the ways of handling biological samples and the necessary control reagents.
  • Describe the established disease biomarkers and their evaluation.

Unit Subjects:

  • Analytical Methodology and Automation in Clinical and Applied Biochemistry – Quality Control
  • Sampling, Preservation, and Properties of Biological Samples
  • Biocatalystsand Hormones in Clinical Biochemistry and Food
  • Disease Biomarkers – Evaluation of Diagnostic Tests

T.U. Grading:

A. Two (2) Written Assignments over the course of the semester, the average grade of which makes up 20% of the final T.U. grade

Β. Four (4) Educational Activities (E.A.) over the course of the semester, the average grade of which makes up 20% of the final T.U. grade.

C. Final Written Examinations (F.W.E.), the grade of which makes up 60% of the final T.U. grade.

Right to participate in the Final Written Examinations:

Students may participate in the Final Written Examinations (F.W.E.) upon the condition that the Written Assignments and Educational Activities referred to in points A and B have been graded with at least 50% of full marks overall for each point.

Prerequisites: There are no prerequisites for this unit.

Teaching Method: Remote learning, utilizing the H.O.U. Remote Learning Platform, and Group Counseling Meetings (remote GCM, in-person GCM).

 

XBA53 CHEMICAL ANALYSIS WORKSHOP

T.U. Code: ΧΒΑ53
Academic Credits (ECTS): 15
T.U. Type: Mandatory Elective
Semester available: Second (2nd) ή Third (3rd)
Language of instruction: Greek

T.U. Objective: The T.L.U. XBA53 aims to provide laboratory training for scientists in the principles, methods, instrumentation, and applications of modern chemical analysis. It aims to familiarize scientists with the modern laboratory and experimental equipment used in chemical analysis, as well as how to use it correctly and effectively.

Learning Outcomes: Upon successful completion of XBA53, students will be able to:

  • Describe laboratory safety regulations
  • Evaluate the experimental results of chemical analyses
  • Statistically process the results of chemical analyses
  • Operate modern laboratory equipment, such as spectrometers, chromatographs, spectrophotometers, diffractometers, fluorimeters etc.
  • Select the most suitable method of analysis for a given application
  • Design and perform classical and modern chemical analysis experimental protocols
  • Apply their skills to solve problems that occur in chemical analysis
  • Make use of analytical instruments and techniques in order to research problems that require chemical analysis in their solution

Unit Subjects:

  • Laboratory Safety Regulations – Statistics, Chemometrics .
  • Modern Chromatographic Techniques
  • Modern Spectrometric Techniques
  • Electroanalytical and Complexometric Techniques
  • Combined Analytical Techniques

Prerequisites: Students who wish to select XBA53 must select it concurrently with XBA50 or have successfully completed XBA50.

Teaching Method: Remote learning, utilizing the H.O.U. Remote Learning Platform, and Group Counseling Meetings (remote GCM, in-person GCM) and five-day practical workshop at the H.O.U. Chemistry Laboratory in Patras.

 

XBA54 BIOMOLECULAR ANALYSIS WORKSHOP

T.U. Code: ΧΒΑ54
Academic Credits (ECTS): 15
T.U. Type: Mandatory Elective
Semester available: Second (2nd) or Third (3rd)
Language of instruction: Greek

T.U. Objective: XBA54 aims to provide laboratory training for scientists in the principles, methods, instrumentation, and applications of modern biomolecular analysis. It aims to familiarize scientists with the modern laboratory and experimental equipment used in biomolecular analysis, as well as how to use it correctly and effectively.

Learning Outcomes: Upon successful completion of XBA54, students will be able to:

  • Describe the quality assurance procedures involved in the experimental protocols used in both service provision and research.
  • Handle biological material and carry out clinical techniques for the isolation and quantitative/qualitative detection of biological macromolecules.
  • Use techniques of detecting and identifying micro-organisms and viruses in biological materials and foods.
  • Detect changes in the genome at the nucleotide base level, as well as biochemical alterations associated with pathological conditions.
  • Use immunochemical methods relevant to clinical diagnosis.

Unit Subjects:

  • Laboratory Biomolecular Analysis Quality Assurance
  • Nucleic Acid and Protein Isolation and Identification Techniques
  • Detection of Contaminants in Biological Materials and Foods
  • Detection of Gene Mutations and Epigenetic Modifications
  • ImmunochemicalMethods

Prerequisites: Students who wish to select the T.L.U. XBA54 must select it concurrently with either XBA51 or XBA52 or have successfully completed both XBA51 and XBA52.

Teaching Method: Remote learning,utilizing the H.O.U. Remote Learning Platform,and Group Counseling Meetings (remote GCM,in-person GCM) and five-day practical workshop at the H.O.U. Chemistry Laboratory in Patras.

XBADE POSTGRADUATE DIPLOMA THESIS

T.U. Code: XBADE
Academic Credits (ECTS): 15
T.U. Type: Mandatory
Semester available: Third (3rd)
Language: Greek or English


Objective:
The diploma thesis aims to provide studentswith the opportunity to apply the skills and knowledge gained over the course of the program in researching and discussing a modern issue of chemical or biomolecular analysis or designing a new methodology. Students may approach the issue either through bibliographic research and study combined with theoretical or computational quantitative and qualitative methods, or through experimentation by applying theory in practice to solve an analysis problem, improve an existing method of analysis, or implement a new methodology..

Prerequisites: Students must first complete the three (3) T.U.: XBA50, XBA51, and XBA52, as well as one (1) of the two (2) T.L.U.: XBA53 or XBA54 in order to begin preparing their PDT. Students may only present and defend their PDT after successfully completing all the T.U. in the Program.

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