Hadjinicolaou Maria

Hadjinicolaou Maria


School of Science and Technology

Applied Mathematics Laboratory, D1- B6



Curriculum Vitae

Maria Hadjinicolaou is a Professor of Applied Mathematics at the School of Science and Technology of the Hellenic Open University (HOU) since 2015. She has received her BA from the Department of Mathematics of the University of Patras (1985) and her PhD in Applied Mathematics from Department of Chemical Engineering, University of Patras (1993). He holds a postgraduate training certificate of the EAP in “Open and Distance Education” (1999).

She has served as an Associate Professor at the School of Science and Technology (SST) of the HOU, 2000-2015, and as an Assistant Professor, (P.D. 407/80), at the University of Ioannina, in the Department of Environmental and Natural Resources Management, 1998-2000. She was a research fellow and teaching associate at the School of Technological Applications of TEI of Patras in the departments of: Mechanical Engineering, Electrical Engineering and Civil Engineering,1996-2000, while during 1993-1998 she was a Post-Doctoral Research Fellow at FORTH, Research Institute of Chemical Engineering and High Temperature Processes, FORTH /IChE and at the Department of Mechanical and Aeronautical Engineering of the University of Patras. During her doctoral studies (1988-1993) she was a graduate Scholar at FORTH /IChE

She is the founder and Director of the Applied Mathematics Laboratory at HOU (2016), founder of the Study Programme “Graduate Studies in Mathematics”, (2003) and Director of Studies for the academic years 2005-2011 and 2012-2015. Since 2015 she is acting as Director for the “Studies in Natural Sciences” Programme, and since 2019 Director for the joint Master’s Programme “Neuroinformatics and Bioinformatics” serving also as the Head of its Scientific and Advisory Committee. She is also the Coordinator of Mathematical Thematic Units of the above Programmes, where she teaches by applying distance education methodologies.

She has supervised 9 doctoral theses, 4 complete, 3 postdoctoral research fellowships, as well as 14 diploma theses. Her research work is depicted in over 68 publications in prestigious international scientific journals and proceedings of international conferences. She has contributed to the concept, methodological design and implementation of 18 research and 3 development programs, funded by the European Union and other sources, in 3 of which she was the PI. She has been an invited speaker in international and national conferences and seminars. She is a member of organizational and scientific committees of international conferences, a member of international and Greek scientific associations, eg. ΑMS, EMS, EME, ELEBIT, She also acts as a reviewer for international scientific journals, as a member of international committees for evaluating research proposals/projects.

Administrative positions/projects

Maria Hadjinicolaou has been the President of the HOU Library and Information Center Committee since 2004, contributing to its design and development. She is representative of the HOU in the International Council of Distance Education, and in the Association of Greek Academic Libraries (HEAL) where he has been elected as a member of its Board of Directors (2019-2022). She is a member of the Internal Assessment Committee of SST (2019-present), while from May 2022 she is a member of the Gender Equality Committee (E.I.F.) of the HOU

She was the Dean of SST during 2013-2016 and 2007-2010, and deputy Dean 2006-2007, while in 2016 she was an deputy member of the HOU Advisory Board. She was a member of the Scientific Committee of the Laboratory of Educational Materials and Educational Methodology 2008-2012, a member of the EAP Ethics Committee, 2014-2015, Secretary of the Scientific Committee of the Hellenic Network for Distance Education, 2004-2009, P.I. for the World Mathematical Olympiad IMO 2004 project, held in Delphi.

Extensive CV on the website: https://www.eap.gr/wp-content/uploads/2022/10/HADJINICOLAOU-M-CV-10-22-2.pdf

Research Interests

Development of mathematical models at multiple scales, for biomedical sciences and continuum engineering problems, such as:

  • Blood flow in vessels and arteries, in the cardiovascular and cerebral systems, transport of medicinal substances,
  • development and use of non-invasive techniques for medical diagnosis and control (behavior of red blood cells and lipoproteins in the blood plasma)
  • Tumor growth and moving boundary problems,
  • Shape recognition and reconstruction from imaging methods,
  • Stokes flow in porous media,
  • Propagation and scattering of waves (direct and inverse problems) by single and multiple scatterers of different physical characteristics and geometric shapes,
  • Behavior and properties of solid materials at the nanoscale (graphene) and macroscale, under different mechanical loads.
  • Process of learning
  • STEM and STEAM education.

Mathematical Methods:

  • Solving Partial Differential Equations, (semiseparation and R-semiseparation of variables),
  • Spectral decomposition of mathematical physics tensors and expansions of eigenfunctions in curvilinear coordinate systems (spheroidal, inverted spheroidal, bispherical, ellipsoidal, etc.)
  • Initial and Boundary value problems
  • Theory of representations in small Reynolds number hydrodynamics,
  • Asymptotic analysis and special functions
  • Transformations in convex and non-convex geometries,
  • Seal method,
  • Perturbation theory
  • Boundary layer theory, .
  • Fractional calculus


Virtual educational “environments” and ICT tools for distance teaching of mathematics.

Extensive CV on the website: https://www.eap.gr/wp-content/uploads/2022/10/HADJINICOLAOU-M-CV-10-22-2.pdf

Teaching experience

Μ. Hadjinicolaou has taught applying distance education methodologies, at EAP, since 2000 until today

  • At the undergraduate level: Linear Algebra, Ordinary Differential Equations, Differential and Integral Calculus of one and many variables, Vector analysis, and applications.
  • At graduate level: Partial Differential Equations, Integral Equations, Linear Algebra and Functional Analysis Topics.
  • "Transportation Phenomena", "Mathematical Analysis, Differential and Integral Calculus" University of Ioannina, Department of Environmental and Natural Resources Management, School of Agrinio,
  • "Calculus of one and many variables", "Applied Mathematics", "Computer Programming" at the Technological Educational Institution of Patras, in the departments of Electrical, Mechanical and Civil Engineering, "Air Pollution / Sources and Control of Pollutants", Department of Mechanical and Aeronautical Engineering P. Patron.
  • She has contributed and participated in over of thirty seminars, lectures, courses on Applied Mathematics, Continuum Mechanics, Fluid Mechanics and Wave Scattering.

Educational material

  • She has designed and developed educational material for the Mathematics Department of the HOU and is the author of 3 books: "Introductory concepts of Mathematics", "Linear Algebra" and "Mathematical Models of Medical Physics", vol. II: Aspects of Biology and Mathematical modelling of tumor growth, supplementary teaching material in various types (hypertext).
  • She was scientifically responsible, coordinator and critical reader for the development of EAP educational material.
  • She is a member of the Scientific Coordination and Evaluation Committee of the Kallipos + "Open Academic Electronic Journals" project.

Selective Publications

  • Generalized eigenfunctions and complete semiseparable solutions for stokes-flow in spheroidal coordinates. Dassios G., Hadjinicolaou M. & Payatakes, A. C. 1994., Quarterly of Applied Mathematics, 52, 157-191.
  • Asymptotic solution of stiff PDEs with the CSP method: The reaction diffusion equation. Hadjinicolaou M. & Goussis D. A. 1998., SIAM Journal on Scientific Computing, 20, 781-810.
  • Non-destructive identification of spherical inclusions. Hadjinicolaou M., Advanced Composites Letters, 2000, 25-33.
  • Analytic solution of an exterior Dirichlet problem in a non-convex domain. Baganis G., Hadjinicolaou M. 2009, IMA Journal of Applied Mathematics, 74, 668-684.
  • Stokes flow applied to the sedimentation of a red blood cell. Hadjinicolaou M., Kamvyssas G., Protopapas E. 2015. Quarterly of Applied Mathematics, 73 (2015), 511-523, https://doi.org/10.1090/qam/1390
  • Unsteady fluid flow in a slightly curved pipe: A comparative study of a matched asymptotic expansions solution with a single analytical solution. Messaris G.A.T., Hadjinicolaou M., Karachalios G.T., 2016. Physics of Fluids 28, 081901 (2016); https://doi.org/10.1063/1.4960432 (Selected for special publication from AIP publishing house, as one among the best 10 out 1200 papers of the American Institute of Physics journals.)
  • Wrinkling formation in simply-supported graphenes under tension and compression loadings. C Androulidakis, EN Koukaras, MGP Carbone, M. Hadjinicolaou, 2017, Nanoscale 9 (46), 18180-1818
  • Hadjinicolaou M., Protopapas E. 2020. A Microscale Mathematical Blood Flow Model for Understanding Cardiovascular Diseases. Springer Advances in Experimental Medicine and Biology 1194, 373-387, doi.org/10.1007/978-3-030-32622-7_35
  • Ampatzoglou P., Kariotou F., Hadjinicolaou M., 2021, A Multiscale Mathematical Model for Tumor Growth, Incorporating the GLUT1 Expression. Advances in Experimental Medicine and Biology, 2021; 1338:273-281. Springer, Cham doi: 10.1007/978-3-030-78775-2_32.
  • Virtual Class – An Appropriate Environment for Distance Learning Mathematics at an Open University. Hadjinicolaou M. 2014., European Journal of Open, Distance and e-learning, http://www.eurodl.org/?p=current&sp=brief&article=620
Skip to content